On the north side of Piazza Sisto V stands the palace of the illustrious Lady Camilla, sister of Pope Sisto V, on whose foundations the Seminary would later be built. On the clock tower, to the left, is the inscription “Time is money,” an aphorism by the German writer and Nobel laureate Thomas Mann; to the right: “Pray and work,” the ora et labora of Saint Benedict of Nursia, and A.M.D.G., Ad maiorem Dei gloriam (“For the greater glory of God”), a phrase first found in the Dialogues of Saint Gregory the Great and later adopted by Saint Ignatius of Loyola for the Society of Jesus.

Today, the former Seminary is undergoing major restoration work and houses the Sistine Episcopal Museum of Sacred Art, where precious liturgical vestments, artistic liturgical objects, reliquaries, paintings, portraits of the Bishops of the Diocese of Montalto, and some ancient parchments are preserved.